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Selected Publications
68Ga-Galmydar: Biodistribution and radiation dosimetry studies in rodents.
Sivapackiam J, Laforest R, Sharma V.
Nucl Med Biol. 2017 Dec 1;59:29-35 PMID: 29454148
 
67Ga-metalloprobes: monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cells.
Sivapackiam J, Harpstrite SE, Rath NP , Sharma V.
Med Chem Comm. 2017,8, 158-161 PMID: 26924499
 
Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aß) in Alzheimer’s Disease.
Sundaram GS, Dhavale DD, Prior JL, Yan P, Cirrito J, Rath NP, Laforest R, Cairns NJ, Lee JM, Kotzbauer PT, Sharma V.
Scientific Reports volume 6, Article number: 35636 (2016). PMID: 27805057
 
Metalloprobes: Fluorescence imaging of multidrug resistance (MDR1) P-Glycoprotein (Pgp)-mediated functional transport activity in cellulo.
Sundaram GS, Sharma M, Kaganov D, Cho J, Harpstrite SE, Sharma V.
J Inorg Biochem. 2016 Feb 26;159:159. PMID: 27031494
 
(67/68)Galmydar: A metalloprobe for monitoring breast cancer resistance protein (BCRP)-mediated functional transport activity.
Sivapackiam J, Harpstrite SE, Prior JL, Mattingly S, Sharma V.
Nucl Med Biol. 2016 Mar;43(3):191. PMID: 26924499
 
Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer's disease
Sundaram GS, Dhavale D, Prior JL, Sivapackiam J, Laforest R, Kotzbauer P, Sharma V.
EJNMMI Res. 2015 Dec;5(1):112. PMID: 26061601
Free PMC article available PMCID: PMC4478171
 
A Generator-Produced Gallium-68 Radiopharmaceutical for PET Imaging of Myocardial Perfusion
Sharma V, Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath NP, Piwnica-Worms D
PLoS One. 2014 Oct 29, 9(10): e109361 PMID: 25353349
Free PMC article available PMCID: PMC4212944
 
Characterization of a Brain Permeant Fluorescent Molecule and Visualization of Aβ Parenchymal Plaques, Using Real-Time Multiphoton Imaging in Transgenic Mice
Sundaram GS, Garai K, Rath NP, Yan P, Cirrito JR, Cairns NJ, Moo-Lee J, Sharma V
Org Lett. 2014, 16(14): 3640-3643 PMID: 25003699
 
Interrogation of multidrug resistance (MDR1) P-glycoprotein (ABCB1) expression in human pancreatic carcinoma cells: correlation of 99mTc-Sestamibi uptake with western blot analysis
Harpstrite SE, Gu H, Natarajan R, Sharma V
Nuc Med Comm. 2014, 35(10): 1067-1070 PMID: 25036383
 
A New Nucleoside Analogue with Potent Activity against Mutant sr39 Herpes Simplex Virus-1 (HSV-1) Thymidine Kinase (TK)
Sundaram GS, Harpstrite SE, Kao JL, Collins SD, Sharma V
Org Lett. 2012, 14(14): 3568-3571 PMID: 2276027
 
Synthesis, molecular structure, and validation of novel metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport
Sivapackiam J, Harpstrite SE, Prior JL, Gu H, Rath, NP, Sharma V
Dalton Trans. 2010, 39: 5842-5850 PMID: 20505882
 
Radiopharmaceuticals for assessment of multidrug resistance P-glycoprotein-mediated drug transport activity
Sharma V
Bioconjugate Chem. 2004, 15(6): 1464-1474 PMID: 15546216
 
Noninvasive imaging of protein-protein interactions in living animals
Luker GD, Sharma V, Pica CM, Dahlheimer JL, Li, W, Ocheskey JA, Ryan CE, Piwnica-Worms H, Piwnica-Worms D
Proc. Natl. Acad. Sci. USA 2002, 99: 6961-6966 PMID: 11997447
Free PMC article available PMCID: PMC124511
 
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